Dr. M.C. (Maria) Cuellar Soares

T: +31 15 27 89856 E: M.C.Cuellar@remove-this.tudelft.nl Room 2.511
Julianalaan 67
2628 BC Delft
The Netherlands                           



  • 2008 - present
    Assistant professor in BioSeparation Technology group, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology
  • 2004 - 2008
    PhD, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology. Thesis title: 'Towards the integration of fermentation and crystallisation - a study on the production of L-Phenylalanine'. Supervisors: Prof. Dr. Ir. L.A.M. van der Wielen (Bioseparation technology group) and Prof. Dr. Ir. J.J. Heijnen (Bioprocess technology group)
  • 2001 - 2003
    Postgraduate program Bioprocess Engineering (PDEng - cum laude), Delft University of Technology
  • 1999 - 2000
    Assistant in Research and Development, Café de Colombia (National Federation of Coffee Growers of Colombia)
  • 1993 - 1999
    Degree in Food Engineering (cum laude), Universidad de Bogotá Jorge Tadeo Lozano, Colombia

Research interests

  • Systematic design of integrated bioprocesses for the production of bulk chemicals and fuels
  • Novel process concepts and equipment for integrated fermentation and separation
  • Integration of tools for microorganism development and process design 

Teaching activities

  • MSc course "Transport & Separation" (Biochemical Engineering program)
  • Until 2014 I have supervised 2 PhD projects, 1 Postdoc, 7 PDEng individual design projects, 2 PDEng group design projects and more than 15 MSc/BSc end projects.

Key publications

  • Cuellar, MC, Wielen, LAM van der (2015). Recent advances in the microbial production and recovery of apolar molecules. Current Opinion in Biotechnology, 33, 39-45.
  • Heeres, AS, Picone, CSF, Wielen, LAM van der, Cunha, RL, Cuellar, MC (2014). Microbial advanced biofuel production: overcoming emulsification challenges for large-scale operation. Trends in Biotechnology, 32 (4), 221-229. dx.doi.org/10.1016/j.tibtech.2014.02.002
  • Cuellar, MC, Heijnen, JJ , Wielen, LAM van der (2013). Large-scale production of diesel-like biofuels - process design as an inherent part of microoorganism devlopment. Biotechnology Journal, 8 (6), 682-689. dx.doi.org/10.1002/biot.201200319
  • Cuellar, MC, Straathof, AJJ, van de Sandt, EJAX, Heijnen, JJ, van der Wielen, LAM. (2010). Conceptual evaluation of integrated process configurations for the recovery of L-phenylalanine product crystals during fermentation. Industrial & Engineering Chemistry Research, 49, 682-689. dx.doi.org/10.1021/ie901007g
  • Cuellar, MC, Herreilers, SN, Straathof, AJJ, Heijnen, JJ & Wielen, LAM van der (2009). Limits of operation for the integration of water removal by membranes and crystallization of L-Phenylalanine. Industrial & engineering chemistry research, 48, 1566-1573. dx.doi.org/10.1021/ie8012659
  • Cuellar, MC, Zijlmans, TW, Straathof, AJJ, Heijnen, JJ & Wielen, LAM van der (2009). Model-based evaluation of cell retention by crossflow ultrafiltration during fed-batch fermentations with Escherichia coli.
    Biochemical engineering journal, 44, 280-288. 


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