Dr.ir. R. (Robbert) Kleerebezem

T: +31 15 27 81091
E: R.Kleerebezem@remove-this.tudelft.nl

Room 0.461
Julianalaan 67
2628 BC Delft
The Netherlands





  • 2006 - present
    Assistant professor, Section of Environmental Biotechnology, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology, The Netherlands
  • 2001 - 2006
    Post-doc researcher, Section of Environmental Biotechnology, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology
  • 1999 - 2000
    Post-doc researcher, Department of Chemical Engineering, University of Santiago de Compostela, Spain, and Department of Enzymology, Moscow State University, Russia
  • 1999
    PhD Environmental Technology, Wageningen University, The Netherlands, Prof. G. Lettinga, ‘Anaerobic degradation of phthalates, Microbiological and Technological Aspects’
  • 1992 - 1998
    PhD student and Researcher, Department of Environmental technology, Wageningen University, The Netherlands
  • 1992
    MSc Environmental Sciences, Wageningen University, The Netherlands

Research interests

  • Microbial community engineering for the production chemicals and bioenergy
  • Microbial carbon, nitrogen and sulphur cycle
  • Thermodynamics and kinetics of microbial processes in natural and man-made ecosystems

Teaching activities

  • BSc and MSc programmes: fermentation technology, scale up/down, metabolic engineering, systems biology, analysis of metabolic networks
  • International Advanced Courses: microbial physiology and fermentation technology, environmental biotechnology, thermodynamics
  • Supervised 8 PhD’s until 2008

Key publications

  • Kleerebezem, R., Van Loosdrecht, M.C.M. (2008) Thermodynamic and kinetic characterization using process dynamics: Acidophilic ferrous iron oxidation by Leptospirillum ferrooxidans. Biotechnology and Bioengineering, 100 (1), pp. 49-60. 
  • Rodríguez, J., Kleerebezem, R., Lema, J.M., Van Loosdrecht, M.C.M. (2006) Modeling product formation in anaerobic mixed culture fermentations. Biotechnology and Bioengineering, 93 (3), pp. 592-606.
  • Gonzalez-Gil, G., Seghezzo, L., Lettinga, G., Kleerebezem, R., University, W. (2001) Kinetics and mass-transfer phenomena in anaerobic granular sludge. Biotechnology and Bioengineering, 73 (2), pp. 125-134. 
  • Kleerebezem, R., Stams, A.J.M. (2000) Kinetics of syntrophic cultures: A theoretical treatise on butyrate fermentation. Biotechnology and Bioengineering, 67 (5), pp. 529-543.
  • Kleerebezem, R., Hulshoff Pol, L.W., Lettinga, G. (1999) Anaerobic degradation of phthalate isomers by methanogenic consortia. Applied and Environmental Microbiology, 65 (3), pp. 1152-1160.


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