Dr.ir. J-M. G. (Jean-Marc) Daran

T: +31 15 27 82412
E: J.G.Daran@remove-this.tudelft.nl

Room 1.030
Julianalaan 67
2628 BC Delft
The Netherlands

 

 


Biography

  • 2003 - present
    Assistant professor, Industrial Microbiology Group, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology, The Netherlands
  • 2001 - 2003
    DSM Food Specialties, Delft, The Netherlands, Scientist, Research and Development, Molecular Genetics and Strain Improvement
  • 1997 - 2001
    DSM Food Specialties, Seclin, France, Scientist, Research and Development, Genetics and Strain Improvement
  • 1996 - 1997
    University of Manchester, United Kingdom, Post-doctoral researcher, Institute of Science and Technology
  • 1992 - 1995
    PhD Yeast molecular physiology group, National Institute of Applied Sciences, Toulouse, France, Prof. J-M. François, 'Genetic and biochemical characterization of the UGP1 gene encoding the UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae: its implications in the intermediary metabolism and cell wall synthesis'
  • 1990 - 1992
    Engineer Diploma, National Institute of Applied Sciences, Toulouse, France
  • 1990
    MSc Biochemistry and Molecular Genetics, Université Paul Sabatier Toulouse III, France

Research interests

  • Genomics of Industrial Organisms
  • Molecular Engineering of Industrial Microorganisms
  • Metabolism of flavour compounds in S. cerevisiae.

Teaching activities

  • MSc programme: Molecular Biotechnology
  • International Advanced Courses: Applied Genomics of Industrial Fermentation
  • Supervising (and supervised) a total of 6 PhD’s until 2008

Key publications

  • Van Den Berg, M.A., Albang, R., Albermann, K., Badger, J.H., Daran, J.-M., M Driessen, A.J., Garcia-Estrada, C., Fedorova, N.D., Harris, D.M., Heijne, W.H.M., Joardar, V., W Kiel, J.A.K., Kovalchuk, A., Martín, J.F., Nierman, W.C., Nijland, J.G., Pronk, J.T., Roubos, J.A., Van Der Klei, I.J., Van Peij, N.N.M.E., Veenhuis, M., Von Döhren, H., Wagner, C., Wortman, J., Bovenberg, R.A.L. Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum (2008) Nature Biotechnology, 26 (10), pp. 1161-1168.
    dx.doi.org/10.1038/nbt.1498
  • Tai, S.L., Daran-Lapujade, P., Walsh, M.C., Pronk, J.T., Daran, J.-M. Acclimation of Saccharomyces cerevisiae to low temperature: A chemostat-based transcriptome analysis (2007) Molecular Biology of the Cell, 18 (12), pp. 5100-5112.
    dx.doi.org/10.1091/mbc.E07-02-0131
  • Daran-Lapujade, P., Rossell, S., Van Gulik, W.M., Luttik, M.A.H., De Groot, M.J.L., Slijper, M., Heck, A.J.R., Daran, J.-M., De Winde, J.H., Westerhoff, H.V., Pronk, J.T., Bakker, B.M. The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels (2007) Proceedings of the National Academy of Sciences of the United States of America, 104 (40), pp. 15753-15758.
    dx.doi.org/10.1073/pnas.0707476104
  • Kresnowati, M.T., van Winden, W.A., Almering, M.J., ten Pierick, A., Ras, C., Knijnenburg, T.A., Daran-Lapujade, P., Pronk, J.T., Heijnen, J.J., Daran, J.M. When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation (2006) Molecular systems biology [electronic resource], 2, p. 49.
    dx.doi.org/10.1038/msb4100083
  • Tai, S.L., Boer, V.M., Daran-Lapujade, P., Walsh, M.C., De Winde, J.H., Daran, J.-M., Pronk, J.T. Two-dimensional transcriptome analysis in chemostat cultures: Combinatorial effects of oxygen availability and macronutrient limitation in Saccharomyces cerevisiae (2005) Journal of Biological Chemistry, 280 (1), pp. 437-447.
    dx.doi.org/10.1074/jbc.M410573200

 

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